After upgrading our hosts to ESXi 6.0 U1, none of our Veeam jobs would run. After much searching, we found out that SSLv3 is disabled by default and is the reason the jobs weren’t completing. There are a couple of KBs describing the issue, but the quick and fast solution for us was to add the following at the end of each host’s /etc/vmware/config.
vmauthd.ssl.noSSLv3 = false
Source: vSphere 6.0 U1 | view topic